Analysis of Various Treatment Methods of Granulomatous Lobular Mastitis (NCT06565845) | Clinical Trial Compass
RecruitingNot Applicable
Analysis of Various Treatment Methods of Granulomatous Lobular Mastitis
China350 participantsStarted 2024-08-19
Plain-language summary
Granulomatous lobular mastitis (GLM) is a rare benign breast disease that is difficult to distinguish from breast cancer based on clinical and imaging findings, and there is currently no standard treatment. This study aims to analyze the clinical characteristics and demographic data of GLM patients and to compare the overall effectiveness of three treatment methods: surgery alone, triple anti-tuberculosis drug therapy alone, and combined surgery with triple anti-tuberculosis drug therapy, with the goal of providing new insights for clinical treatment.
Who can participate
Age range
15 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* non-lactating and aged 15-65 years
* histopathological confirmation of GLM
* normal liver and kidney function
Exclusion Criteria:
* lactating and pregnant women
* allergies to rifampin, isoniazid, or ethambutol
* concurrent malignant breast tumors
* severe underlying diseases
* other conditions deemed unsuitable by the investigator and
* refusal to participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Differences in the cure rate of the three treatment modalities
Timeframe: Baseline
2
Differences in the recurrence rate of the three treatment modalities
Timeframe: Baseline
3
Differences in the incidence of adverse reactions of the three treatment modalities
Timeframe: Baseline
Trial details
NCT IDNCT06565845
SponsorFirst Affiliated Hospital of Harbin Medical University