CompletedNot Applicable

The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues

Thailand30 participantsStarted 2024-02-10

Plain-language summary

Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome. Therefore, an increased effectiveness of TKE is interesting for physical therapy implication. Besides, adding sensory input which is audible cues or rhythm during exercise may enhance the efficacy of the exercise by increasing neuromuscular control and function. Therefore, the study aimed to investigate the immediate effects of combined TKE with audible cues on motor unit behavior. The researchers expect that adding rhythm from the metronome will enhance neuromuscular control which may change motor unit behavior of VM muscle. The findings of the study may have helped explain the mechanism behind the acute effects of combined TKE with audible cues on VM function and their potential application in the field of physical therapy. This study aims to investigate the immediate effect of combined TKE with audible cues on motor unit behavior in healthy participants and to investigate reliability of decomposition electromyography procedure during single leg squat.

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged range between 18 and 30 years * BMI of 18.5-25 kg/m2 * Male or female * Lightly active or sedentary {Physical activity level (PAL= 1.4-1.69)} Exclusion Criteria: * History of serious injury or operation of lower back and lower extremities such as fracture * Musculoskeletal problems of lower back and lower extremities in 6 months before the study * Single-leg stance test \< 43 seconds (26). and range of weight-bearing lunge test \< 9.1 cm

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Motor unit firing rate

Timeframe: At the end of Cycle 1 (each cycle is 1 day)

Peak motor action potential

Timeframe: At the end of Cycle 1 (each cycle is 1 day)

Trial details

NCT IDNCT06565325

SponsorMahidol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-07

View on ClinicalTrials.gov More Muscle Weakness trials