RecruitingNot Applicable

A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)

United States40 participantsStarted 2024-08-02

Plain-language summary

This study is a non-interventional, observational study that will evaluate the natural history of corneal abrasions in patients with Dystrophic Epidermolysis Bullosa (DEB).

Who can participate

Age range6 Months

SexALL

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Inclusion criteria

✓. The subject or their respective legal guardian must have read, understood, and signed an Institutional Review Board (IRB) approved Informed Consent/Assent Form and must be able to and willing to follow study procedures and instructions.
✓. Age 6 months or older at time of Informed Consent/Assent.
✓. Prior genetic diagnosis of DEB due to mutation(s) in the collagen type VII alpha 1 chain (COL7A1) gene.

What they're measuring

Corneal abrasion frequency

Timeframe: Baseline through up to 1 year

Trial details

NCT IDNCT06563414

SponsorKrystal Biotech, Inc.

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2025-12

Contact for this trial

David Chien, MD

412-586-5830 dchien@krystalbio.com

View on ClinicalTrials.gov More Epidermolysis Bullosa Dystrophica trials