Active — Not RecruitingNot Applicable

The Basophil Activation Test For Egg Allergy

China174 participantsStarted 2024-08-10

Plain-language summary

In this study, basophil activation test (BAT) established by the investigators' lab was evaluated for its sensitivity and specificity in child egg allergy diagnosis. Children with suspected IgE mediated allergy to egg will be recruited in the study. Specific IgE to egg allergen and BAT will be detected. The diagnostic accuracy of the BAT will be assessed against clinical diagnosis based on history, clinical symptoms and laboratory results.

Who can participate

Age range4 Months – 6 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

* 1.Children older than 4 months and younger than 6 years old * 2.Suspected egg allergy with one or more of the following complaints after intake of egg: Skin or mucous symptoms (e. g. urticaria, increased eczema, or swollen lips) Respiratory symptoms (tight throat or shortness of breath with signs of bronchial obstruction) loss of consciousness Gastrointestinal symptoms (nausea, vomiting, abdominal pain, diarrhea) Ocular symptoms (conjunctival erythema, pruritus, tears) and other related symptoms * 3\. Sign informed consent by parents/guardians Exclusion Criteria: * 1.Patients with hematological tumors, autoimmune diseases, organ transplantation, and immunodeficiency diseases * 2.Take immunosuppressants, immunomodulators, statins, and inject anesthetics within 3 weeks

What they're measuring

Sensitivity of the BAT

Timeframe: 2 days

Specificity of the BAT

Timeframe: 2 days

Trial details

NCT IDNCT06559319

SponsorXia Peng

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-03-25

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