Ageing BIOmarker Study in Singaporeans (NCT06555978) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Ageing BIOmarker Study in Singaporeans
Singapore378 participantsStarted 2021-03-12
Plain-language summary
The Ageing BIOmarker Study in Singaporeans (ABIOS) aims to understand the biological aging processes and how they affect health among people in Singapore. As people grow older, their risk of developing chronic diseases increases. This study aims to better understand the biological changes that come with age, particularly in three major ethnic groups: Chinese, Malay, and Indian adults over 21 years old. By examining a range of health indicators such as DNA methylation, inflammation, metabolism, cardiovascular health, physical function, and physical activity (i.e., molecular, physiological, and digital biomarkers of ageing), the study seeks to identify how ethnicity, lifestyle, and socioeconomic factors influence ageing. This unique study focuses on an all-Asian population, aiming to enhance our understanding of healthy aging across different ethnic groups.
Who can participate
Age range
21 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* ≥21 years of age
* Chinese, Malay, or Indian and has lived in Singapore for at least 5 consecutive years
* Apparently healthy and non-smokers
* Having only 1 condition (if ≥45 and \<65 years) or any condition (if ≥65 years), and all conditions were medication-controlled (if any):
* Hypertension
* Hyperlipidemia
* Hyperglycemia
* Osteopenia/osteoporosis
* Osteoarthritis
* Type 2 diabetes
Exclusion Criteria:
* Body mass index (BMI) ≥30 kg/m\^2
* Pre-existing or history of major cardiovascular disease (e.g., coronary artery disease, heart failure, stroke, peripheral vascular disease)
* Any metal implants (excluding dental implants) in the body
* Pre-existing or history of cancer or chronic obstructive pulmonary disease (COPD)
* Pregnant women or planning pregnancy in the next 6-12 months
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.