Active — Not RecruitingNot Applicable

The Importance of Insulin Action in the Brain for the Immune System During Physical Activity

Germany20 participantsStarted 2024-12-15

Plain-language summary

The goal of this clinical trial is to clarify the interaction of central insulin action and physical activity with the immune system. Therefore, participants will undergo bicycle spiroergometer tests. This approach will be compared between days with insulin delivery to the brain as nasal spray and days with placebo spray.

Who can participate

Age range18 Years – 30 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * BMI \< 24 kg/m2 * no known primary diseases * hormonal contraception with a single-phase preparation Exclusion Criteria: * Alcohol or drug abuse * Smoking * At screening: Hb \< 12 g/dl for women and Hb \< 14 g/dl for men * Any (clinical) condition that would endanger participant's safety or question scientific success according to a physician's opinion.

What they're measuring

Immune system activation

Timeframe: 120 minutes

Immune system activation

Timeframe: 120 minutes

Trial details

NCT IDNCT06552130

SponsorUniversity of Ulm

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-14

View on ClinicalTrials.gov More Insulin Sensitivity trials