CompletedPhase 4

IV PAPAVERINE Prior to Propess for Labor Induction

Israel110 participantsStarted 2024-08-12

Plain-language summary

The investigators aim to evaluate the effect of administering papaverine prior to PGE2 insertion on changes in Bishop-scores and on the induction-to-delivery interval. Researchers will compare drug papaverine to a placebo

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * singleton term pregnancy * bishop score * need for labor induction with PGE2 * vertex presentation * viable fetus Exclusion Criteria: * Prelabour rupture of membrane * Twins pregnancy * previous cesarean section * allergy to the study medication * fetal anomaly contraindications for vaginal delivery * maternal supraventricular tachicardia

What they're measuring

Delta Bishop score

Timeframe: 24 hours

the time from propess insertion until delivery

Timeframe: 72 hours

Trial details

NCT IDNCT06550232

SponsorWestern Galilee Hospital-Nahariya

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2025-03-23

View on ClinicalTrials.gov More Induced Vaginal Delivery trials