CompletedNot Applicable

Diagnosis and Staging of Typhoid Fever Using Surface-enhanced Raman Spectroscopy Liquid Biopsy

Germany30 participantsStarted 2023-07-15

Plain-language summary

The goal of this project is to adapt the gold nanoparticle-based surface-enhanced Raman spectroscopy (SERS) technology to clinical application. In this exploratory study a measurement protocol will be established to subsequently investigate whether SERS allows to diagnose patients infected with typhoid fever as well as to stage the disease.

Who can participate

Age range18 Years – 70 Years

SexALL

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Inclusion Criteria: * Patient at Nishtar Medical University * The age range of the patients was from 18 to 70 years * Confirmed disease with the Widal test (for typhoid fever groups) Exclusion Criteria: * Patients with severe concurrent diseases were excluded from the study

What they're measuring

SERS measurements to differentiate between healthy and typhoid fever patients

Timeframe: Through study competition, up to 1 year

Trial details

NCT IDNCT06546982

SponsorUniversity Hospital, Aachen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-08-15

View on ClinicalTrials.gov More Typhoid Fever trials