Polyphenol-rich Haskap berries (Haskap) have untapped therapeutic potential to improve human health, and agricultural producers in northern U.S. states are poised to increase production if consumer demand increases. A critical knowledge gap is that little is known about the interactions between gut microbes and Haskap polyphenols to produce bioactive metabolites linked to downstream health impacts. Additionally, little is known about which Haskap varieties and harvest timing yield the greatest bioactive potential. This study aims to address these gaps by investigating the interaction of bioactive components in Haskap with gut microbiota and the resultant gut and serum metabolites, inflammation, and metabolic health, and then couple this with analysis of berries from different Haskap varieties and harvest times.
Age range
35 Years – 65 Years
Sex
ALL
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16 subunit ribosomal ribonucleic acid (16S rRNA) gut microbial composition
Timeframe: 8 weeks
Inflammation (pg/mL)
Timeframe: 8 weeks
Lipid Panel (mg/dL)
Timeframe: 8 weeks
F2 isoprostanes
Timeframe: 8 weeks
Untargeted metabolomic analysis
Timeframe: 8 weeks
Untargeted metabolomic analysis
Timeframe: 8 weeks
Exercise Induced Fat Oxidation
Timeframe: 8 weeks