CompletedNot Applicable

Risk Factors for Adverse Outcomes in Sepsis

China10,313 participantsStarted 2003-01-01

Plain-language summary

This study will adopt a retrospective clinical cohort design and include a certain scale of sepsis patients as research objects to find the risk factors for adverse outcomes in patients with sepsis. Bioinformatics techniques were used to infer potential differential genes corresponding to different risk factors. Finally, through the biobank the investigators established in the past, biological samples of patients with sepsis were extracted and protein expression in the samples was detected to comprehensively analyze biological information at multiple levels.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * over 18 years old; * meet the diagnostic criteria for sepsis; * Duration of hospitalization: lasting more than 24 hours; * no important comorbidities, such as heart failure, liver and kidney insufficiency, malignant tumor, etc. * Antibiotic use: The time to start antibiotic treatment should not exceed 48 hours. Exclusion Criteria: * less than 18 years old; * Clinical anti-infective therapy: Start long-term anti-infective therapy within 14 days before the expected time point of infection; * Duration of hospitalization: less than 24 hours; * The presence of other important complications, such as heart failure, liver and kidney insufficiency, and malignant tumors; * The presence of other important complications, such as heart failure, liver and kidney insufficiency, and malignant tumors; * The presence of other infectious diseases, such as tuberculosis, HIV/AIDS, etc.

What they're measuring

Survival

Timeframe: 28 days

Cardiac function

Timeframe: 24 hours

Trial details

NCT IDNCT06541600

SponsorQin Zhang

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-01-01