CompletedNot Applicable

Influence of Verbal Suggestion on the Therapeutic Effect of the Joint Manipulation

Poland64 participantsStarted 2024-10-14

Plain-language summary

The aim of the study is to evaluate the influence of verbal suggestion on the therapeutic effect of the joint manipulation of the lumbar spine in patients with chronic non-specific low back pain in relation to the pain level, stress, disability, function, sleepiness, tissue temperature and selected blood biochemical markers. The study participants will be randomly assigned (sealed allocation envelopes) to the following groups: * Group A (test intervention + placebo communication) * Group B (test intervention + nocebo communication) * Group C (test intervention + neutral communication) The study will mainly consist of the three stages, i.e. before the intervention, immediately after the intervention and 24 hours later.

Who can participate

Age range

19 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * participants with low back pain lasting more than 3 months, * participants who have not been taking any non-steroidal anti-inflammatory drugs (NSAIDs) for at least one week prior to the start of the study, * participants who are not taking any steroid drugs, * participants who have never had the joint manipulation before, * participants within the age range of 19-30 years, * written consent to participate in the study. Exclusion Criteria: * participants who are students of physiotherapy, * participants with a BMI \>33, * participants after a lumbar spine surgery, * participants who, in the 6 months prior to the start of the study, suffered from a lumbar spine injury, * participants with diabetes, * participants with rheumatic diseases, * participants with endometriosis, * participants with endocrine diseases, * participants with acute inflammation in the lumbar spine region and sciatica symptoms.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Numerical Rating Scale (NRS)

Timeframe: Before the intervention, immediately after the intervention and 24 hours later

Trial details

NCT IDNCT06537739

SponsorJohn Paul II University in Biała Podlaska

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-16

View on ClinicalTrials.gov More Back Pain trials