The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcomes at two years corrected age. This is based on the hypothesis that infants in MPV arm are expected to experience the greatest benefit compared with infants receiving standard care.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bayley-4 language performance (SA3 primary outcome)
Timeframe: 2 years corrected age
Amygdala volume on MRI (SA1a, primary outcome)
Timeframe: At term-equivalent (~ 3 months of age), 37-41 weeks postmenstrual age (PMA)
Intranetwork connectivity in Salience and Language networks (SA2a, primary outcome)
Timeframe: Term-equivalent (~ 3 months of age), 37-41 weeks postmenstrual age (PMA)