UnknownNot Applicable

Comparison of Efficacy and Safety Between Ciprofol and Remimazolam During Fiberoptic Bronchoscopy

190 participantsStarted 2024-12-01

Plain-language summary

Both ciprofol and remimazolam have been found to be potential alternatives to propofol (a commonly used anesthesia) during fiberoptic bronchoscopy, while the efficacy and safety between ciprofol and remimazolam have not been reported. This study aims to compare the efficacy and safety between ciprofol and remimazolam in patients undergoing fiberoptic bronchoscopy.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. male or female patients with age ≥ 18 years old;
. scheduled to undergo bronchoscopy under laryngeal mask airway;
. with American Society of Anesthesiologists (ASA) physical status classes II to Ⅲ; and
. volunteering to participate in this study and signing an informed consent form.

Exclusion criteria

. with contraindications to deep sedation/general anesthesia or with a history of sedation/anesthesia accidents;
. allergic to eggs, bean products, or experimental drugs (ciprofol, sufentanil, or remimazolam);
. difficult airway;
. with bradycardia or other serious cardiovascular diseases;
. with severe damages or diseases in important organs such as the lungs, brain, liver, or kidneys;
. using sedatives or antidepressants for a long time;
. pregnant or lactating women; and (8) unable to communicate or cooperate.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The success rate of fiberoptic bronchoscopy

Timeframe: 24 hours after fiberoptic bronchoscopy

Trial details

NCT IDNCT06531915

SponsorAnhui Provincial Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2024-12-30

View on ClinicalTrials.gov More Fiberoptic Bronchoscopy trials