Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL R… (NCT06529692) | Clinical Trial Compass
RecruitingNot Applicable
Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction
United States9 participantsStarted 2025-08-13
Plain-language summary
The goal of this study is to gather pilot data to help inform a future clinical trial. As such, the investigators will employ a randomized clinical trial design, but data will only be collected on 9 total subjects. Nine subjects will be randomized to 2 split-belt intervention groups (one group where early stance loading is trained and the other where midstance loading is trained) and a placebo group.
The goal of this study is to explore the adaptations in knee loading from a 6-week split-belt training intervention.
The investigators' main question for this aim is:
1. Does knee loading, measured by the sagittal plane knee moment, change to a greater extent in the split-belt treadmill training groups compared to the placebo group?
2. Are there differences in training-related knee loading changes between individuals trained in the early stance vs. midstance loading split-belt training?
Who can participate
Age range
14 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* aged 14-45 years
* suffered an acute, complete ACL rupture as confirmed by MRI and physical exam
* have undergone ACL reconstruction w autograft within the past 10 months
* willingness to participate in testing and follow-up as outlined in the protocol
* English-speaking
Exclusion Criteria:
* inability to provide written informed consent
* female subjects who are pregnant or are planning to become pregnant (self-reported)
* previous ACL injury
* previous surgery to either knee
* bony fracture accompanying ACL injury
* patients who experienced a knee dislocation
* patients who had their ACL reconstructed with an allograft
* patients who underwent a multi-ligamentous and/or staged ACL reconstruction
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
ACL Leg Sagittal Plane Knee Moment
Timeframe: Before training, midway through training (3 weeks), & after training (6 weeks)