AI ECG TIMI is an investigator-initiated, international, and multicenter registry of acute coronary syndrome patients aimed to identify electrocardiographic findings detected by an AI model predicting coronary blood flow alteration. The aim of the study is to identify electrocardiographic findings detected by an automated artificial intelligence (AI) model that can predict coronary blood flow alteration as assessed by the TIMI grade flow at the very moment of the invasive coronary angiography in patients with acute coronary syndromes.
Who can participate
Age range
18 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with acute coronary syndromes undergoing invasive coronary angiography as clinically indicated.
* Availability of a standard 12-lead ECG performed at invasive coronary angiogram before percutaneous coronary intervention (maximum within 15 min before vascular access).
* Age ≥18 years.
Exclusion Criteria:
* Individuals presenting for a non-emergent (elective) cardiac catheterization.
* Individuals presenting with chronic coronary syndrome (CCS) or stable angina symptoms.
* Individuals without symptoms suspicious for acute coronary syndromes.
* Individuals with contraindications for cardiac catheterization.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing an AI tool that reads ECGs to detect blocked blood flow in acute coronary syndrome — if I come in with chest pain, is this AI-ECG system being used at this hospital, and could it affect how quickly my blocked artery gets identified?
2Since this study is listed as 'active not recruiting,' does that mean the AI-ECG tool is still being evaluated and not yet approved for routine use, and should I be asking whether my ECG is being read by a doctor, the AI, or both?
3The trial focuses on STEMI and NSTEMI separately — given which type of ACS I have, how confident is my care team in detecting which specific artery is blocked using current standard ECG methods, and would an AI-assisted reading add anything for my situation?
4The primary goal here is measuring how accurate this AI model is at diagnosis — so at this stage, does my doctor feel the evidence is strong enough to trust it as part of my treatment decisions, or is it still primarily a research tool?
5If this AI-ECG approach eventually proves accurate, how might it change the speed or strategy of getting me to the cardiac catheterization lab, and is that something worth factoring into where I seek emergency care?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Diagnostic Accuracy of the AI-ECG TIMI AI Model
Timeframe: Index hospitalization (assessed up to 5 days)