CompletedNot Applicable

Nasoseptal Double Flap Versus Rescue Flap in Endoscopic Transsphenoidal Pituitary Surgery

Egypt56 participantsStarted 2022-12-12

Plain-language summary

This paper investigates the outcomes of two surgical techniques-nasoseptal double flap and nasoseptal rescue flap-used in endoscopic transsphenoidal surgery for pituitary tumors. The nasoseptal flap technique has significantly reduced the incidence of postoperative Cerebrospinal Fluid (CSF) leaks but can cause nasal morbidity.

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All consecutive patients with symptomatic pituitary macroadenoma * Tumor size ≥ 2 cm Exclusion Criteria: * -Absent sphenoid pneumatization. * Temporal or frontal extension. * Recurrent pituitary tumor after previous surgery. * Previous nasal surgery. * Associated nasal disease e.g. rhinosinusitis. * Unfit for general anesthesia. * Refusal of surgical intervention or signing consent.

What they're measuring

Nasal morbidity

Timeframe: at baseline preoperative and 1 month and 3 months postoperative.

Trial details

NCT IDNCT06526481

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-26

View on ClinicalTrials.gov More Pituitary Adenoma trials