Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)

Inclusion Criteria: * Age ≥18 * Participants are willing and able to comply with the protocol, including undergoing data and samples collection as well as study visits and examinations. * Signed informed consent form * In possession of a Healios+Me app compatible smartphone (iOS/Android) * Corrected close visual acuity of ≥0.5 * Hand motor skills sufficient for using a smartphone * Ability to follow the study procedures * Diagnosed with MS according to the revised McDonald criteria 2017, all clinical forms inclusive (clinically isolated syndrome, RRMS, SPMS, PPMS) AND early disease stages (\< 3 years) OR transitioning phase to progressive disease as evaluated based on Expanded Disability Status Scale (EDSS). * Enrolled in the SMSC at University Hospital Basel There are no specific exclusion criteria.