This study aimed to examine the effect of Tiotropium, which is used in the treatment of COPD, on eye symptoms.The study was conducted prospectively. Patients were examined in three groups. Thirty-six patients were included in each group in the study. Anterior chamber parameters, intraocular pressure values, and photopic-mesopic pupil diameters were measured at the initial visit for Group 1 and Group 2 patients, and at the third month of treatment for Group 3 patients.
Who can participate
Age range
47 Years – 82 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Clinical diagnosis of COPD
. Not receiving any COPD treatment
. Receiving only 18 mcg Tiotropium treatment
. With written consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at whether tiotropium — a common COPD inhaler — can narrow the eye angles and raise pressure inside the eye, so if I'm being considered for tiotropium, should I get a baseline eye exam first to check whether I already have narrow angles or early glaucoma?
2Since the trial specifically measured angle-closure as a concern, does my personal eye anatomy put me at higher risk for this kind of reaction to tiotropium, and should I see an ophthalmologist before starting it?
3The trial is completed — can you share what the findings actually showed about intraocular pressure and pupil changes, and how that affects whether tiotropium is still a safe choice for my COPD treatment?
4Are there other COPD inhalers or medications that work differently from tiotropium and wouldn't carry the same potential eye risks, especially if I already have any signs of glaucoma?
5If I do start tiotropium, what warning signs in my vision — like blurred sight, eye pain, or halos around lights — should prompt me to call you or go to the emergency room right away?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Tiotropium causes narrowing of the eye angles and an increase in intraocular pressure and pupil diameters.
Timeframe: Measurements were made in the third month of Tiotropium treatment.