Effects of Inspiratory Muscle Training on Lymphedema (NCT06521268) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Effects of Inspiratory Muscle Training on Lymphedema
Turkey (Türkiye)24 participantsStarted 2025-07-01
Plain-language summary
The aim of this study is to examine the effect of inspiratory muscle training on lymphedema volume, subcutaneous tissue thickness, upper extremity functionality and sleep quality in the treatment of upper extremity lymphedema. Two groups included 24 patients with lymphedema will be divided into gropus (intervetion and control) and they will compare each other.
Who can participate
Age range
18 Years – 60 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Having been diagnosed with lymphedema in the upper extremity at least 6 months ago
* Having stage 2 lymphedema
* Having a 2-8 cm circumference difference between the affected extremity and the healthy extremity at any reference point
* Being between the ages of 18-60
* Voluntarily agreeing to participate in the study
* Not having received any lymphedema treatment in the last 6 months.
* Not having any physical, respiratory, neurological and/or systemic disease that would prevent participation in the treatment program.
Exclusion Criteria:
Having stage 1 and stage 3 lymphedema
* It has been less than 6 months since the diagnosis of lymphedema was made
* Being under 18 years of age and over 60 years of age
* Having a circumference measurement difference of more than 8 cm and less than 2 cm at any reference point between the affected extremity and the healthy extremity
* Lymphedema or elephantiasis with papilloma, hyperkeratosis
* Uncontrolled hypertension, pulmonary edema, presence of serious cardiovascular disease
* Presence of active metastasis
* Acute inflammatory diseases
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Volumetric Measurement
Timeframe: baseline and immediately after the intervention (in the 5th week)
2
Measurement of Subcutaneous Tissue Thickness with Ultrasound (US)
Timeframe: baseline and immediately after the intervention (in the 5th week)