CompletedNot Applicable

Prediction Model of Microvascular Ischemic Ocular Motor Nerve Palsy and Inflammatory Ocular Motor Nerve Palsy in Chinese Patients

China299 participantsStarted 2020-01-01

Plain-language summary

This study aimed to train and validate deep learning systems (DLS) to differentiate between microvascular ischemic ocular motor nerve palsy (v-OMNP) and inflammatory ocular motor nerve palsy (i-OMNP). The method involves using clearly diagnosed v-OMNP and i-OMNP patients from the Department of Neurology database at Beijing Tongren Hospital for further DLS validation, aiding in the differential diagnosis of the aforementioned diseases.

Who can participate

Age range18 Years

SexALL

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Exclusion criteria

✕. Inclusion Criteria:
✕. Sudden onset of unilateral CN III, CN IV, or CN VI palsy.
✕. Isolated CN III (without pupil involvement), CN IV, or CN VI palsy.
✕. Presence of vascular risk factors (VRFs).
✕. Significant symptom recovery no earlier than 2 months after onset, with complete (or nearly complete) recovery within 3-6 months.
✕. Unilateral painful CN III, CN IV, and/or CN VI palsy.
✕. Symptoms (including pain or diplopia signs) significantly improved within 72 hours after treatment with corticosteroids.
✕. MRI of the cavernous sinus showing inflammation, i.e., abnormal widening/enhancement of the affected cavernous sinus with or without granulomatous changes/inflammatory manifestations of adjacent tissues.

What they're measuring

The diagnosis of acute bilateral diplopia, microvascular ischemic ocular motor nerve palsy or inflammatory ocular motor nerve palsy.

Timeframe: 6 months

Trial details

NCT IDNCT06518096

SponsorBeijing Tongren Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-07-31

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