RecruitingNot Applicable

Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10

Belgium142 participantsStarted 2024-05-03

Plain-language summary

To date, there are no methods for assessing the risk of oral developmental defects that could predict long-term adverse effects in childhood cancer survivors. Having such a method at our disposal would enable us to better assess the risk to develop those defects and will help us provide new prevention and treatment strategies to ensure a healthy oral development. The aims of this study are : * Assess the caries risk in childhood cancer survivors compared with a control group. * Assess the dental development defects risk in childhood cancer survivors compared with a control group.

Who can participate

Age range12 Years – 36 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age below 10 at cancer diagnosis (for the CCS group). * Chemotherapy must have been used to treat the patient (For the CCS group). * The patient is 12 years old or older at the time of the follow-up appointment of the present study Exclusion Criteria: * A patient who was diagnosed and treated after 10 years old. * Patient below 12 years old at time of study recruitment * Patients with syndrome or diseases that involve teeth impairment\* * Pregnant patient * Refusal or inaptitude to undergo dental and radiographic examination

What they're measuring

Assessment of the caries experience by using the Decay Missing Filled Teeth score (DMFT)

Timeframe: Thoughout the entire study, approximately during 2 years

Trial details

NCT IDNCT06517927

SponsorCliniques universitaires Saint-Luc- Université Catholique de Louvain

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-03

Contact for this trial

Armand IRAKOZE

027645741 armand.irakoze@uclouvain.be