By InvitationNot Applicable

Movement Control and Motor Unit Behavior Responses to Different Types of Stimulation

Thailand136 participantsStarted 2024-07-01

Plain-language summary

This study aims to determine the effect of different stimulations including 1) transcranial direct current stimulation (tDCS), 2) neuromuscular electrical stimulation (NMES), 3) motor control exercise (MCE), and 4) isometric exercise (IE) on movement control and motor unit behavior in individuals with movement control impairment, and determine the correlation between movement control and motor unit behavior.

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Between the ages of 18 and 40
✓. Both male and female
✓. Presence of movement control impairment (instability catch during clinical observation of active forward bend test)
✓. No current episode of low back pain
✓. No definitive neurologic signs including weakness or numbness in the lower extremity
✓. No previous spinal surgery
✓. Have not been diagnosed osteoporosis, severe spinal stenosis, inflammatory joint disease, and/or systemic disease
✓. Body mass index (BMI) less than 30 kg/m2

Exclusion criteria

✕. Pregnancy
✕. Any lower extremity condition that would potentially alter trunk movement in standing
✕. Vestibular dysfunction
✕. Extreme psychosocial involvement
✕. Active treatment of another medical illness that would preclude participation in any aspect of the study
✕. Contraindication for tDCS including a history of head injury/surgery, seizure, cardiac pacemaker, metal/electrical/magnetic implantation, uncontrolled migraine headache

What they're measuring

Segmental angular velocity in degrees/second

Timeframe: baseline and immediately after the intervention

Clinical observation

Timeframe: baseline and immediately after the intervention

Number of motor units

Timeframe: baseline and immediately after the intervention

Motor unit action potential in millivolts

Timeframe: baseline and immediately after the intervention

Motor unit firing rate in pulses/second

Timeframe: baseline and immediately after the intervention

Trial details

NCT IDNCT06516770

SponsorMahidol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06

View on ClinicalTrials.gov More Low Back Pain trials

Plain-language summary

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Between the ages of 18 and 40
✓. Both male and female
✓. Presence of movement control impairment (instability catch during clinical observation of active forward bend test)
✓. No current episode of low back pain
✓. No definitive neurologic signs including weakness or numbness in the lower extremity
✓. No previous spinal surgery
✓. Have not been diagnosed osteoporosis, severe spinal stenosis, inflammatory joint disease, and/or systemic disease
✓. Body mass index (BMI) less than 30 kg/m2

Exclusion criteria

✕. Pregnancy
✕. Any lower extremity condition that would potentially alter trunk movement in standing
✕. Vestibular dysfunction
✕. Extreme psychosocial involvement
✕. Active treatment of another medical illness that would preclude participation in any aspect of the study
✕. Contraindication for tDCS including a history of head injury/surgery, seizure, cardiac pacemaker, metal/electrical/magnetic implantation, uncontrolled migraine headache

What they're measuring

Segmental angular velocity in degrees/second

Timeframe: baseline and immediately after the intervention

Clinical observation

Timeframe: baseline and immediately after the intervention

Number of motor units

Timeframe: baseline and immediately after the intervention

Motor unit action potential in millivolts

Timeframe: baseline and immediately after the intervention

Motor unit firing rate in pulses/second

Timeframe: baseline and immediately after the intervention