Inferior Vena Cava Collapsibility and Distensibility Assessment in Critical Care. (NCT06516692) | Clinical Trial Compass
CompletedNot Applicable
Inferior Vena Cava Collapsibility and Distensibility Assessment in Critical Care.
Pakistan180 participantsStarted 2024-08-01
Plain-language summary
This study will help in determining the impact of assessment of Inferior Vena Cava Collapsibility and Distensibility Index (IVC CI and DI) through Point Of Care Ultra Sound (POCUS), for the fluid management of critically ill patients. This would help in better management of such patients in resource limited countries, where costly equipment for cardiac output monitoring and fluid management are frequently not available.
Moreover this study will help in development of future guidelines for fluid resuscitation in critically ill patients.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients admitted in critical care with systolic Blood Pressure \< 90 mmHg with any of the diagnosis as per operational definition:
* Sepsis
* Diabetic ketoacidosis
* Acute kidney injury
* Acute gastroenteritis
Exclusion Criteria:
* Known case of right heart disease
* Known case of congestive cardiac failure
* Presence of marked ascites
* IVC could not be identified or diameter could not be measured
* Pregnant females
* Body Mass Index (BMI) \>30 Kg/meter2
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Within 24-hours, 7-day and 28 day mortalities
Timeframe: Mortalities will be assessed and recorded within 24hour, then day 7 up to 28th day.
2
Cumulative fluid balance
Timeframe: At 6 hours of enrolment of participant
3
Change in Sequential Organ Failure Assessment score(Δ SOFA)