Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions (NCT06515977) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions
2,964 participantsStarted 2024-08-01
Plain-language summary
Texture and Color Enhancement Imaging (TXI) is a newly developed image-enhancing endoscopy technology that has show potential in improving detection of colorectal lesions. This multicenter, randomized, tandem trial is aimed at evaluating whether TXI is superior to WLI endoscopy in terms of diagnosis of premalignant lesions.
Who can participate
Age range
45 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
patients aged 45-85 years and scheduled for screening colonoscopy who provided written informed consent
Exclusion Criteria:
Surveillance, diagnostic or therapeutic colonoscopy
Patients with an already known or suspected colorectal tumour
Patients with alarming symptoms and signs, including haematochezia, melena, weight loss or anaemia without specific causes, an abdominal mass and positive digital rectal examination
Pregnant or lactating women
Patients with gastrointestinal tract obstruction
Patients with inflammatory bowel diseases, hereditary CRC syndromes or serrated polyposis syndrome
Patients with abnormal blood coagulation or taking antiplatelets or anticoagulants within 7 days before colonoscopy
Patients with failed cecal intubation
Patients with poor bowel preparation quality that necessitated a second bowel preparation
Patients with a history of colonic resection
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.