CompletedPhase 1

Assessment of the Remineralization Efficacy of Vitamin D in the Treatment of MIH and Its Role in Improving Oral Hygiene and Gingival Health. In Situ Randomized Double-Blind Placebo CT

Egypt32 participantsStarted 2024-08-30

Plain-language summary

In child patients with molar incisor hypo mineralization, Will Vitamin D mouth wash offer more success for patients with MIH as regards better MIH TNI index, decrease plaque accumulation, more gingival health and less bleeding on probing differentiated from placebo mouthwash?

Who can participate

Age range6 Years – 12 Years

SexALL

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Inclusion criteria

✓. More than 6 years' child with all permanent incisors and first molar teeth are fully erupted with all surfaces visible.
✓. At least one affected first permanent molar were considered to have MIH (Lygidakis et al. 2010; Kühnisch et al. 2014).
✓. No chronic systemic disease
✓. No acute infection
✓. cooperative Child

Exclusion criteria

✕. Drugs (chlorhexidine-based gels and mouthwashes)
✕. Hypomineralization with a diameter less than 1 mm.
✕. Hypoplastic defects, fluorosis (diffuse hypomineralization), amelogenesis imperfecta, and dentinogenesis imperfecta.
✕. Defects on approximal surfaces and diffuse opacities.
✕. Fixed orthodontic treatment

What they're measuring

MIH TNI

Timeframe: 3 months

Gingival Index

Timeframe: 3 months

Plaque Index

Timeframe: 3 months

Trial details

NCT IDNCT06515548

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-01

View on ClinicalTrials.gov More Molar Incisor Hypomineralization trials