CompletedNot Applicable

Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean Section

Egypt48 participantsStarted 2023-11-27

Plain-language summary

comparison between oral sumatriptan and Nebulized Dexmedetomidine in Post Dural Puncture Headache in Cesarean Section

Age range18 Years – 40 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Pregnant female aged between 18 and 40 years old.
✓. ASA II and III undergoing elective caesarean section.
✓. Diagnosed with Postdural puncture headache with visual analogue score (VAS) ≥ 4 and Lybecker classification score ≥ 2.

✕. Patient refusal.
✕. History of primary headaches such as migraine, cluster and tension headaches.
✕. Hypersensitivity of dexmedetomidine or sumatriptan.
✕. Hypertensive disorders of the pregnancy.
✕. Contraindication to spinal anesthesia as coagulopathy or infection at site of injection.
✕. Symptoms of ischemic heart disease (IHD) e.g. angina.
✕. Cerebrovascular disease e.g. stroke or transient ischemic attacks (TIAs).
✕. Using of Monoamine oxidase inhibitors (MAOIs) in the last 24h.

visual analogue scale

Timeframe: First 48 hours

NCT IDNCT06514040

SponsorFayoum University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-08-15