Early Diagnosis of Acute Renal Failure by Urine Trehalase Levels. (NCT06505655) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Early Diagnosis of Acute Renal Failure by Urine Trehalase Levels.
Turkey (Türkiye)40 participantsStarted 2024-07-15
Plain-language summary
We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method, and thus, early diagnosed acute renal failure can be treated quickly and patients can be protected from subsequent complications in the postoperative period.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Being over the age of 18 and under the age of 65
* Having signed the BGOF form to be included in the study,
* Being in ASA 1 or ASA 2 classification
* Not having kidney failure or kidney disease
* No history of single kidney or renal transplantation
* Not using nephrotoxic drugs or agents before surgery
* Renal function tests taken preoperatively should be within normal ranges.
* No urinary tract infection or urinary problems (such as polyuria, oliguria or anuria)
Exclusion Criteria:
* Those under the age of 18 or over the age of 65
* Those who do not want to participate in the study
* ASA 3 and above
* Having previously received treatment for kidney disease - including kidney stones -
* Having been previously diagnosed with acute or chronic renal failure
* Having a single kidney or a history of renal transplantation
* Using nephrotoxic drugs or agents (such as contrast material) before surgery
* Kidney function tests taken preoperatively are not within normal ranges
* Having a urinary tract infection or urinary problem (such as polyuria, oliguria or anuria)
* Having a history of kidney stones, acute renal failure or chronic renal failure
* Those with active infection or disease before surgery
* They were determined as patients for whom consent was not obtained for the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.