RecruitingNot Applicable

Chronic Nonspecific Neck Pain and Central Nervous System Focused Treatment Program

Turkey (Türkiye)30 participantsStarted 2024-07-10

Plain-language summary

Neck pain is one of the most common musculoskeletal pain disorders secondary to low back pain. Pharmacological and non-medical treatments such as physiotherapy are applied in its treatment. Patients with chronic nonspecific neck pain (CNSP) can be treated with various interventions such as drug therapy, manual therapy, heat and exercise. However, it is also reported that chronic pain occurs as a result of neuroplasticity, that is, the brain learning pain through the central synthesis mechanism in the central nervous system. For this reason, although the importance of central nervous system-oriented therapies is increasing day by day, this system-oriented therapies are still ignored in clinics. Therefore, in this master's thesis study, it is aimed to investigate the effects of central nervous system-focused therapies (pain neuroscience education, breathing exercises and relaxation exercises with guided imagery) on pain, range of motion, functional status, pain-related fear, anxiety, depression and quality of life in addition to traditional physiotherapy applied to patients with CNSP.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Being diagnosed with nonspecific neck pain by a doctor, * To be between the ages of 18-65, * Having neck pain for more than 3 months * No previous neck or shoulder surgery, * No shoulder pain due to any cause, * A tumour or inflammatory disease underlying the neck pain not to be found, * A clinically underlying stenosis or discogenic problem not to be present. * Negative results from the following clinical examination tests; * Spurling test, * Lhermitte test, * Cervical distraction test, * Adson test, Exclusion Criteria: * Not meeting the inclusion criteria, * Positive neurological examination (positive motor presence, reflex or sensory abnormalities indicating spinal root compression) or abnormal neurological findings related to nerve compression in the upper limb * Systemic rheumatological or metabolic diseases or cancer * Refusal to participate in the study, * Failure to complete treatment, * Having any neurological problem * Severe psychological illnesses

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The Numerical Rating Scale (NPRS-11)

Timeframe: Change from baseline range of motion at 4th week

Range of Motion

Timeframe: Change from baseline range of motion at 4th week

Pressure Pain Threshold

Timeframe: Change from baseline range of motion at 4th week

Neck disability index

Timeframe: Change from baseline range of motion at 4th week

Pain Catastrophizing Scale

Timeframe: Change from baseline range of motion at 4th week

Fear avoidance belief questionnaire

Timeframe: Change from baseline range of motion at 4th week

Trial details

NCT IDNCT06503562

SponsorAcibadem University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-11-10

Contact for this trial

Nuray ALACA

05324251290 nuray.alaca@acibadem.edu.tr

View on ClinicalTrials.gov More Neck Pain trials

Plain-language summary

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

The Numerical Rating Scale (NPRS-11)

Timeframe: Change from baseline range of motion at 4th week

Range of Motion

Timeframe: Change from baseline range of motion at 4th week

Pressure Pain Threshold

Timeframe: Change from baseline range of motion at 4th week

Neck disability index

Timeframe: Change from baseline range of motion at 4th week

Pain Catastrophizing Scale

Timeframe: Change from baseline range of motion at 4th week

Fear avoidance belief questionnaire

Timeframe: Change from baseline range of motion at 4th week