Efficacy of Serratus Posterior Intercostal Plane Block for Analgesia and Inflammatory Marker in Breast Surgery

Inclusion Criteria: * Adults undergoing unilateral breast surgery under general anesthesia * Age 21 to 60 years with body mass index (BMI)=18 to 25 kg/m2 * American Society of Anesthesiologists (ASA) grade I-III. Exclusion Criteria: * Patients with Long-time use of analgesic drugs * Past history of chest surgery, * Allergy to local anesthetics, * Systemic infection, * Cognitive and language disorders precluding participation, * Patients with coagulopathy,anticoagulant users * hemodynamic unstable patients * Patients with neurology, spinal, psychiatry diseases * infection at block site * patients refused to participate in the study .