The Impact Of Different Final Irrigation Activation Techniques On Postoperative Pain (NCT06501703) | Clinical Trial Compass
CompletedNot Applicable
The Impact Of Different Final Irrigation Activation Techniques On Postoperative Pain
Egypt70 participantsStarted 2024-06-01
Plain-language summary
The trial was conducted to assess the impact of passive ultrasonic irrigation, XP endo finisher, AF max file, and manual dynamic agitation on postoperative pain and analgesic consumption at 6 h., 12 h., 24 h., 48 h., 72 h., and a week later on single-rooted lower premolar teeth with acute irreversible pulpitis and apical periodontitis.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* solitary-rooted lower premolar teeth with acute irreversible pulpitis and apical periodontitis who were in the age range between 18 and 40 years old.
* Each patient received root canal treatment in one session.
* restorable teeth with a normal periodontal score index of less than two
* severe preoperative pain (Vas score 3)
* discomfort response on biting/mastication or percussion but no mobility.
* Discomfort response on palpation of surrounding tissue but with no intraoral swelling.
* Patients who stopped medications for the last 12 hours before the procedure
* The radiograph showed only normal or slight widening in the periodontal ligament space of the affected root.
Exclusion Criteria:
* patients with any serious systemic disease
* Patients under the age of eighteen or incapable of giving informed consent
* Patients over forty
* Patients with a mandibular premolar involving multiple canals or huge periapical pathosis
* Patients with severe preoperative pain on biting/mastication or percussion
* Mandibular premolar with open apices
* Mandibular premolar with periodontal involvement
* Retreated cases, sinus tract presence, and swelling of surrounding soft tissues
* patients who had been pregnant and allergic patients with local anesthetic agents
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The Impact Of Different Final Irrigation Activation Techniques On Postoperative Pain
Timeframe: 6, 12, 24, 48, 72 hours and I week after completion of root canal treatment.