Not Yet RecruitingEarly Phase 1

Evaluation of the Effect of Intra-ligamentary Injection of Diclofenac Potassium Versus Articaine on Anaesthetic Efficacy in Mandibular Molars With Symptomatic Irreversible Pulpitis.

40 participantsStarted 2024-08

Plain-language summary

This study aims to assess the effect the intraligamentary injection of Diclofenac Potassium versus Articaine 4% on the anaesthetic efficacy \& intensity of intraoperative \& postoperative pain during single visit root canal treatment in patients with symptomatic irreversible pulpitis in mandibular molar teeth

Who can participate

Age range18 Years – 55 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

✕. Patients allergic to anesthetic solutions \& other NSAIDs.
✕. Pregnant or nursing females.
✕. Patients having significant systemic disorder (ASA III or IV).
✕. Gastrointestinal disorders.
✕. If the initial diagnosis revealed pain in more than one tooth.
✕. Hemostatic disorders or anti-coagulant therapy during the last month.
✕. Consumption of opioid or non-opioid analgesics or NSAIDs during the last 12 hours before treatment.
✕. Teeth that have:

What they're measuring

Efficacy of local anesthesia

Timeframe: intraoperative ( access cavity preparation & instrumentation ) during root canal treatment

Trial details

NCT IDNCT06500871

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05

Contact for this trial

Mai Eldeeb, master

01093738532 mai.eldeeb@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Teeth With Acute Irreverseble Pulpitis trials