HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men (NCT06498505) | Clinical Trial Compass
RecruitingPhase 4
HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men
Kyrgyzstan270 participantsStarted 2024-07-15
Plain-language summary
Randomized clinical trial evaluating the effect of acetazolamide on pulmonary artery pressure in women compared to men travelling to 3600 m.
Who can participate
Age range18 Years – 44 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Healthy, non-smoking men and women, age 18-44 years, without any diseases and need of regular medication (including oral contraceptives).
* BMI \>18 kg/m2 and \<30 kg/m2
* Born, raised and currently living at altitudes \<1000 m
* Written informed consent
* Premenopausal women with an eumenorrheic cycle
Exclusion Criteria:
* Other types of contraceptvies (hormonal intrauterine device, vaginal ring, subcutaneous injections or implants, among others)
* Pregnancy or nursing
* Anaemic (haemoglobin concentration \<10g/dl)
* Any altitude trip \<4 weks before the study
* Allergy to acetazolamide and other sulfonamides