WithdrawnPhase 2

Prescribing Lorazepam for IUD Insertion: Pilot Feasibility Study

Stopped: Unable to coordinate logistics

United States0Started 2025-10

Plain-language summary

The objective of this pilot study is to discuss the feasibility of prescribing lorazepam prior to IUD insertion and of measuring effect of lorazepam on anxiety and pain with Intrauterine Device (IUD) insertion. The target population for this study will be 25 adult participants scheduled for an IUD insertion at a UW Family Medicine residency clinic. Participants will be followed for 1 appointment visit.

Who can participate

Age range

18 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants who undergo IUD insertion and complete the visual analogue scales to rate their anxiety and pain level prior to the procedure and after the procedure. * Participants must have a driver take them to their appointment if they take lorazepam prior to their arrival at the clinic. * Participants must have a driver take them home after the procedure as well. * Participants must consent to email communication since they will sign the consent forms electronically Exclusion Criteria: * Participants who do not show up for their appointment. * Participants who receive cervical blocks or other analgesic method during IUD insertion. * Participants who have a history of substance use disorder. * Participants who are taking medications with a central nervous system (CNS) depressant effect (ex: opioids, benzodiazepines). * Participants who are not able to sign an electronic consent form. * Participants who do not have a driver to take them to their appointment and to take them home after the procedure. * Participants who do not agree to sign consent forms electronically.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Visual Analogue Scale for Pain

Timeframe: before and after the procedure (up to 1 hour)

Visual Analogue Scale for Anxiety

Timeframe: before and after the procedure (up to 1 hour)

Trial details

NCT IDNCT06496854

SponsorUniversity of Wisconsin, Madison

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01

View on ClinicalTrials.gov More Pain trials