Not Yet RecruitingNot Applicable

Electroacupuncture for the Treatment of Agitated Symptoms of Alzheimer's Disease

China224 participantsStarted 2024-07-20

Plain-language summary

The purpose of this study is to evaluate the efficacy of electroacupuncture in the treatment of agitation symptoms in patients with Alzheimer's disease (AD). Meanwhile the study aims to explore the brain central mechanism of electroacupuncture in the treatment of agitation symptoms in patients with AD by using resting state functional magnetic resonance technology.

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Meet the revised draft diagnostic criteria for Alzheimer's disease published by the Alzheimer's Association in 2023
. Meet the 2023 IPA definition of agitated symptoms of cognitive impairment
. Cohen Mansfield Agitation Inventory (CMAI)≥45 points
. Have been on stable anti-AD medication (cholinesterase inhibitors, etc.) for more than 1 month
. If taking antipsychotics, the medication regimen for agitation (antipsychotics) is stable for 1 month prior to randomization
. Subject and legal guardian and caregiver sign informed consent.

Exclusion criteria

. There are contraindications for acupuncture treatment, such as the tendency of acupoint bleeding or allergy to metal

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Cohen Mansfield Agitation Inventory (CMAI)

Timeframe: CMAI will be evaluated after the final treatment at week 8

Trial details

NCT IDNCT06495957

SponsorGuang'anmen Hospital of China Academy of Chinese Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-07-31

Contact for this trial

Baohui Jia

010-88001454 jiabaohui2504@gamyy.cn

View on ClinicalTrials.gov More Agitation Associated With Alzheimer's Dementia trials