CompletedNot Applicable

Comparative Effectiveness of Uterine Repair Surgery on Preventing Recurrence of Cesarean Sar Pregnancy

China606 participantsStarted 2019-01-01

Plain-language summary

The goal of this observational study is to learn about the long-term effects of resection surgery which is cesarean scar pregnancy(CSP) excision plus hysterotomy closure in CSP patients to treat their CSP. The main question it aims to answer is: Does resection surgery lower next recurrence of CSP than conservative surgery which leaves the uterine niche alone? Participants already underwent resection surgery or conservative surgery will answer survey questions about their next pregnancy for 3 years.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion criteria

✓. This retrospective study screened 1027 CSP individuals from the multiple center Medical Record Data System (MRDS) from three large hospitals in China, recorded between Jan 1, 2019, and Dec 31, 2022.
✓. Conservative surgeries included dilatation and curettage (D\&C) and hysteroscopy, and resection surgeries included CSP excision plus hysterotomy closure
✓. Based on the widespread clinical utility of diagnostic criteria, four factors pertaining to patients, namely amenorrhea, clinical manifestations, laboratory results, and 3-D ultrasound or MRI findings, were thoroughly examined.
✓. All participants were subsequently verified pathologically to confirm the presence of CSP.
✓. Chinese CSP classification was selected as investigate group.
✓. The international group encompasses endogenous and exogenous were selected as control group.

Exclusion criteria

✕. those with incomplete medical record information or follow-up data;
✕. those who did not undergo their first surgery at any of the three hospitals;
✕. individuals without fertility requirements or have adopted long-term contraception were excluded;
✕. who underwent surgery after December 31, 2022 were excluded, even if they became pregnant during the follow-up time.

What they're measuring

effectiveness

Timeframe: up to 3 years

Trial details

NCT IDNCT06485180

SponsorWomen's Hospital School Of Medicine Zhejiang University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-31

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