CompletedNot Applicable

Transmasculine Quality of Life and Sexual Function at Pre and Post Gender-affirming Hormonal Therapy

Thailand40 participantsStarted 2022-09-15

Plain-language summary

The goal of this prospective observational study is to evaluate the short-term effect of testosterone therapy on these issues among hormone naïve TM individuals. The main questions that aim to answer are : 1. Comparison quality of life in transgender men at pre and post testosterone therapy 2. To evaluate the most affected domain of quality of life (QOL) and FSFI of this participants Participants will be ask to complete two questionnaires: the World Health Organization Quality of Life BREF THAI (WHO-QOL-BREF-THAI) and the FSFI (female sexual function index) before testosterone administration and both questionnaires will be re-evaluated at 12 weeks after initiation of testosterone therapy

Who can participate

Age range

18 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * compatible with Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) * had never used testosterone therapy before the enrollment Exclusion Criteria: * history of abnormal hormone functions * ongoing treatment or current use of medications that affect hormone functions * diagnosis of psychiatric illnesses beyond gender dysphoria by a psychiatrist * prescription of psychiatric or neurological medications within the past 3 months up to the present study participation * presence of chronic illnesses or severe age-related conditions, such as chronic kidney disease, chronic liver disease, or any type of cancer

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

quality of life from WHOQOLBREFTHAI questionnaire in transgender men after testosterone therapy

Timeframe: 3 months

Trial details

NCT IDNCT06482385

SponsorChulalongkorn University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-05-31

View on ClinicalTrials.gov More Transgender Men trials