CompletedNot Applicable

Estimate the Relationship Between Oral Microbiota and Stroke

China170 participantsStarted 2024-04-01

Plain-language summary

Oral bacteria constitute the second largest population of the human microbiome. Recent studies have identified their role in the development of systemic diseases, such as cardiovascular and cerebrovascular diseases. Streptococcus Mutans (SM) is considered the primary pathogen responsible for dental caries. Furthermore, in cases of oral inflammatory diseases, SM has been found to invade the bloodstream and disseminate, leading to systemic diseases. Against this backdrop, this study aims to investigate disparities in oral flora between stroke patients and healthy individuals by collecting saliva samples from both groups.

Who can participate

Age range18 Years – 90 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 1\. Microbleeding/damage or rupture of small blood vessels in the brain has been diagnosed within the past 365 days 2. Have done nuclear magnetic examination and can provide nuclear magnetic results Exclusion Criteria: * Have received antibiotic quality within the last three months

What they're measuring

Estimate the Relationship Between Oral Microbiota and Stroke

Timeframe: 2025.06

Correlation Between Oral Microbiota and Cerebral Microbleeds in Stroke

Timeframe: 2025.06

Trial details

NCT IDNCT06479915

SponsorFujian Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-02-28

View on ClinicalTrials.gov More Stroke trials