Role of Left Stellate Ganglion Block in Offering Myocardial Protection in On-pump Mitral Valve Re… (NCT06476925) | Clinical Trial Compass
CompletedNot Applicable
Role of Left Stellate Ganglion Block in Offering Myocardial Protection in On-pump Mitral Valve Replacement? A Histopathological and Clinical Assessment
Egypt62 participantsStarted 2024-07-15
Plain-language summary
Can pre-operative left stellate ganglion block offer myocardial protection in on-pump mitral valve replacement? A histopathological and clinical assessment.
Who can participate
Age range
25 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult population of both sex, between 25-50 years, will undergo elective on pump mitral valve replacement
Exclusion Criteria:
* -Combined valve replacement ( mitral and aortic or mitral and tricuspid valves replacement).
* Emergency valve replacement ( stuck valve, infective endocarditis).
* Pre-operative cardiomyopathy (Ejection fraction less than 45%).
* Recent myocardial infarction ( within 6 months)
* Redo mitral valve replacement.
* Pre-operative pacing, or cardioverter, any form arrhythmia ( tachy or brady).
* Previous history of carotid endarterectomy or presence of carotid stent.
* On thrombolytic therapy.
* Severe chronic obstructive airway disease,
* Patient refusal
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of patients with microscopic myocardial injury