There is evidence indicating that sperm plays a role in determining blastocyst ploidy status. In our study, we aim to compare the outcomes of preimplantation genetic testing for aneuploidy (PGT-A) and the subsequent clinical outcomes following transfers of euploid embryos. This comparison will be conducted between cases where ejaculated sperm and cases where testicular sperm were used for intracytoplasmic sperm injection (ICSI), specifically focusing on severe male factor infertility patients.
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Euploidy rate
Timeframe: 15 days post ICSI
Aneuploidy rate
Timeframe: 15 days post ICSI
Low mosaic rate
Timeframe: Time Frame: 15 days post ICSI
High mosaic rate
Timeframe: Time Frame: 15 days post ICSI
Implantation rate
Timeframe: 6-9 weeks post-embryo transfer
Ongoing pregnancy rate
Timeframe: 12 weeks of gestation
Miscarriage rate
Timeframe: after 6 weeks of gestation
Clinical pregnancy rate
Timeframe: 6-9 weeks post-embryo transfer