Venoconstrictive Thigh Cuffs (VTC) are being evaluated to determine the effectiveness at reversing the headward fluid shift that occurs during weightlessness. If successful, future studies may be done to implement these as a CM to SANS. To support this effort, participants will participate in 2 preflight study sessions consisting of a VTC fit check and a baseline data collection without and with the VTC donned. Participants will also participate in 3 inflight study sessions: a VTC fit check on flight day 30 (FD30) and two separate data collection sessions on flight day 45 (FD45) and 45 days before landing (R-45). During the two in-flight data collection days, participants will be studied before and for up to 6 hours after donning the VTC.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Internal Jugular Vein (IJV) area
Timeframe: Thigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return
IJV pressure
Timeframe: Thigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return
Intraocular Pressure (IOP)
Timeframe: Thigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return
stroke volume
Timeframe: Thigh Cuff Measures 90 days before mission, after 45 days in mission, and 45 days before return