Muscle-tendon Interaction in the Spastic Sural Triceps During Gait (NCT06474117) | Clinical Trial Compass
CompletedNot Applicable
Muscle-tendon Interaction in the Spastic Sural Triceps During Gait
France64 participantsStarted 2024-11-15
Plain-language summary
This project aims to study the mechanical behavior of the muscle-tendon unit (MTU) of the gastrocnemius medialis (GM) and the Achilles tendon (AT) in post-stroke and spinal cord injured (SCI) patients compared to a healthy population, focusing on the variations in muscle and tendon length during the stance phase of the gait cycle. The primary objective is to assess the respective contributions of the GM and AT lengthening in the MTU during walking. Inclusion criteria include adult post-stroke and post-SCI patients with voluntary motor function and some walking capacity. Methods include ultrasound measurements and 3D gait analysis.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria :
Post-Stroke Population:
* Adult male or female
* Patient who had a stroke more than 7 days ago
* Patient hospitalized (in conventional hospitalization or day hospital) in the university neurological rehabilitation department of CHU de Nantes
* Patient with voluntary motor function graded between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
* Patient classified between 3 and 8 on the New Functional Ambulation Classification
Post-Spinal Cord Injury Population:
* Adult male or female
* Patient with an incomplete spinal cord injury classified as ASIA AIS C or D from level C2 to L5
* Patient hospitalized (in conventional hospitalization or day hospital) in the neurological rehabilitation department of CHU de Nantes
* Patient with voluntary motor function graded between 2 and 4 on the MRC (Medical Research Council) scale at the GM level
* Patient classified between 3 and 8 on the New Functional Ambulation Classification
Healthy Population:
• Adult male or female without any neurological disorders
Exclusion Criteria :
Post-Stroke and Post-Spinal Cord Injury Population:
* Minor patient
* History of calf surgery, surgery to reduce triceps surae spasticity, or intramuscular injection (e.g., botulinum toxin) in the plantar flexors within the last 6 months
* Patient with a progressive condition contraindicating physical exertion (e.g., syrinx, cardiovascular instability)
* Peripheral pathology of the considered lower limb
Healthy Popu…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Length of the Achilles Tendon (AT), Muscle Fibers of the Gastrocnemius Medialis (GM), and the Muscle GM During the Single Support Phase of Walking