This study aims to investigate the effects of different types of respiratory muscle training on lung function, diaphragm movement, and voice quality in patients with Parkinson's disease (PD). PD often leads to breathing difficulties and voice abnormalities due to weakened respiratory muscles and reduced diaphragm mobility. The study will involve 45 participants with PD, randomly assigned to three groups: one group will perform inspiratory muscle training, the second group will perform both inspiratory and expiratory muscle training, and the third group will receive placebo-controlled expiratory muscle training. The hypothesis is that targeted respiratory muscle training will significantly improve pulmonary function, diaphragm excursion, and phonatory measures compared to the placebo group. The findings aim to develop effective rehabilitation strategies to enhance the quality of life and communication abilities in individuals with PD.
Age range
30 Years – 85 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Forced Vital Capacity (FVC)
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Forced Expiratory Volume in One Second (FEV1)
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Maximal Inspiratory Pressure (MIP)
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Maximal Expiratory Pressure (MEP)
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Peak Expiratory Flow Rate (PEFR)
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Maximum Phonation Time
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Voice Intensity
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Speech Rate
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Speech Pauses
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Voice Loudness
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).
Voice Handicap Index (VHI-10)
Timeframe: Assessments will be conducted at baseline (week 0) and after the intervention period (week 8).