Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies

Inclusion Criteria: * Adults aged 18-60 years old * Current daily cigarette smoker * Able to understand study procedures and provide informed consent * For females, non-pregnant and non-lactating Exclusion Criteria: * Presence of significant uncontrolled medical conditions (e.g. cardiovascular disease, respiratory disorders, cancer) that could affect smoking behaviors or study participation * Presence of major uncontrolled psychiatric disorders (e.g. schizophrenia, bipolar disorder, severe depression) * Current substance use disorder (except nicotine dependence) * Taking medications that could significantly interfere with study objectives (e.g. medications for smoking cessation) * Significant cognitive impairment that precludes ability to complete study procedures