Comparison of Eccentric Exercise and Static Stretching on Muscle Flexibility (NCT06469346) | Clinical Trial Compass
By InvitationNot Applicable
Comparison of Eccentric Exercise and Static Stretching on Muscle Flexibility
Chile42 participantsStarted 2025-03-03
Plain-language summary
Background: Muscle flexibility is a fundamental physical quality for body development, daily life and sports activities, and also for maintaining muscle quality during aging. Limited flexibility leads to an increased prevalence of musculoskeletal injury in general population and longer return to sports activities.
Among the existent strategies to increase muscle flexibility in sports training and physical rehabilitation, static stretching is commonly used by health and physical activity professionals. Its effectiveness in increasing flexibility has been widely demonstrated; however its effects on muscle strength and power remains controversial.
Therefore, eccentric resistance exercise has been proposed as an effective intervention for increasing muscle flexibility through structural changes on muscle architecture (pennation angle and fascicle length) with the additional benefit of resistance training on muscle strength and power. Nonetheless, its unknown if the increase in muscle flexibility through eccentric resistance exercise could be similar to what has been previously demonstrated with static stretching.
Who can participate
Age range
18 Years – 35 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Masculine University students between 18 and 35 years old
* Physically Inactive considering physical activity recommendations from World Health Organization
* Bilateral hamstring muscle stiffness defined as \<160° in passive Knee Extension Angle Test
* Body Max Index 18,5 \< BMI \< 24,9 kg/m2
Exclusion Criteria:
* Lower back and lower limb (hip, thigh, knee, ankle) musculoskeletal injury in the last 12 months.
* Hamstring injury (strain, tendinopathy, tendon avulsion) previously during the period of life
* Dietary anabolic supplements consumption
* Musculoskeletal, cardiovascular, respiratory o similar health condition that limits participation on physical activity programs
* Regular resistance training (2 or more times per week, carrying out progressive training) in the previous 6 months
* Smoker (1 cigarette per day)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.