CompletedPhase 1/2

Efficacy of Hyaluronic Acid in Prevention of Acute Radiation Proctitis

Egypt44 participantsStarted 2024-04-01

Plain-language summary

A randomized placebo-controlled clinical trial to evaluate efficacy of hyaluronic acid in prevention of acute radiation proctitis among oncology patient population especially who are diagnosed with abdomeno-pelvic tumors and subsequently required radiotherapy.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All patients diagnosed with pelvic or gastrointestinal malignancies (tumors in uterus, cervix, prostate, seminal vesicles, kidney, colon, etc.), * All patients who required adjuvant or radical radiation therapy; * Age \< 80 years; * Karnofsky Performance Status ≥ 60 Exclusion Criteria: * Patients were excluded if they had * gt; previous pelvic radiotherapy, * gt; inflammatory bowel disease or * gt; rectal issues (e.g., haemorrhoids). * Patients diagnosed with cancer rectum

What they're measuring

Time (in days) to occurrence of Acute Radiation Proctitis

Timeframe: for each patient: time from the first day of radiation therapy for up to 3 months

Trial details

NCT IDNCT06469216

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-01

View on ClinicalTrials.gov More Acute Radiation Proctitis trials