Sympatholytic Effects of High Thoracic Erector Spinae Plane Block: Changes in Optic Nerve Sheath … (NCT06468384) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Sympatholytic Effects of High Thoracic Erector Spinae Plane Block: Changes in Optic Nerve Sheath Diameter
15 participantsStarted 2024-06-20
Plain-language summary
The thoracic erector spinae plane (ESP) block is suggested to potentially affect the stellate ganglion, a key component of the sympathetic nervous system, thereby influencing autonomic functions. Changes in optic nerve sheath diameter (ONSD) are used as indicators of intracranial pressure changes. This study aims to investigate the effects of the ESP block on ONSD, providing insights into its impact on the stellate ganglion and enhancing the understanding of the ESP block's safety and efficacy.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults with neck, shoulder, and arm pain
* Those with complex regional pain syndrome
The study will include 15 adult patients who are planned to receive T2-ESP block treatment.
* Age between 18-65 years
* Both genders
* ASA physical status I-II
Exclusion Criteria:
* Those who refuse procedures and tests
* Individuals with conditions that can increase intracranial pressure
* Those with severe heart failure
* Individuals with second or third-degree atrioventricular block
* Those with a history of unstable angina
* Individuals with COPD or chronic asthma
* Those who have experienced a myocardial infarction (MI) within the last 6 weeks
* Individuals with a heart rate below 50 beats per minute
* Those with systolic blood pressure below 90 mmHg
* Individuals with liver failure
* Those with kidney failure
* Individuals for whom a supraclavicular block is anatomically impossible
* Those with neurological or psychological conditions that complicate test evaluation
* Individuals allergic to any of the study medications
* Pregnant individuals
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Optic nerve sheath diameter (ONSD)
Timeframe: Before the block and 30 minutes after the block.