Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indi… (NCT06467968) | Clinical Trial Compass
RecruitingNot Applicable
Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indication
France99 participantsStarted 2023-02-02
Plain-language summary
Gallium-68-DOTATOC binds primarily with high affinity to somatostatin subtype 2 (SSTR2) receptors and these somatostatin receptors are also overexpressed on inflammation cells when activated.
The hypothesis is that the GATED mode on a Gallium-68-DOTATOC cardiac recording would be able to highlight abnormalities that could be correlated with the age of the patients and their cardiovascular risk factors.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Persons who have received complete information on the organization of the research and who have signed the informed consent and:
* Age ≥ 18 years old.
* Having read and understood the information document.
* Affiliated to a social security scheme.
Person for whom a 68Ga-DOTATOC PET/CT exam is requested as part of the diagnostic or pre-therapeutic assessment of a neuroendocrine tumour.
Exclusion Criteria:
Person with
* Hypersensitivity during previous use of 68Ga-DOTATOC
* Impossibility of performing a PET-CT (patient agitated, confused, etc.).
* History of heart disease,
* Severe arrhythmia that does not allow the PET synchronized with the ECG
* Severe renal insufficiency (GFR \<30 ml/min/1.73 m2)
* Treated with a somatostatin analogue.
* Cushing's syndrome
* Pregnant woman, likely to be or breastfeeding
* Adult subject to a legal protection measure (guardianship, curators, legal safeguard)
* Person of legal age unable to express their consent
* Person deprived of liberty by a judicial or administrative decision
* Person, subject to psychiatric care under articles L. 3212-1 and L. 3213-1
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Relationship between the captation of radiotracer and the cardiovascular disease