CompletedNot Applicable

Prediction Model for Advanced Gastric Cancer in Elderly

China1,436 participantsStarted 2024-01-01

Plain-language summary

This study aims to develop and validate a Nomogram (mCNS) model for predicting long-term survival in elderly patients following curative resection for advanced gastric cancer. The study is a retrospective multi-center analysis involving 924 gastric cancer patients treated at the Department of Gastrointestinal Surgery of the Affiliated Union Hospital of Fujian Medical University between 2009 and 2013, and 512 patients aged 65 and above who underwent gastric resection at the Affiliated Zhongshan Hospital of Dalian University between 2011 and 2018. An online prognostic tool is introduced to assist clinicians in predicting patient prognosis and customizing treatment and follow-up strategies.

Who can participate

Age range

65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Confirmed as primary gastric adenocarcinoma by preoperative gastric endoscopy pathology; * Underwent R0 laparoscopic radical gastrectomy for gastric cancer; * Pathological stage T2-4a-N+; * Age ≥ 65 years. Exclusion Criteria: * Pathological stage T1 and T2N0; * Age \< 65 years; * Presence of peritoneal or distant metastasis confirmed before or during surgery; * Received neoadjuvant chemotherapy before surgery; * Remnant gastric cancer; * Emergency surgery or palliative exploratory surgery; * Preoperative abdominal CT scan not available or preoperative examination time \> 1 month; * Survival time less than 1 month; * Incomplete clinical and pathological data.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

5-Year Overall Survival

Timeframe: 5 years or 60 months.

Trial details

NCT IDNCT06467591

SponsorChang-Ming Huang, Prof.

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-05-01

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