RecruitingNot Applicable

Prediction of Undesired Obstruction in External Ventricular Drains.

France640 participantsStarted 2024-07-04

Plain-language summary

Acute obstructive hydrocephalus often complicates intraventricular hemorrhage (IVH). The insertion of an external ventricular drain (EVD) is typically necessary in order to alleviate intracranial pressure by draining excess fluid. However, dysfunction of the EVD whether due to malposition or obstruction, can exacerbate hydrocephalus in an already compromised brain. EVD dysfunction must therefore be promptly detected and treated. Consequently, identifying high-risk patients and closely monitoring them is imperative. While IVH is known to increase the risk of obstruction in the natural cerebrospinal fluid outflow tract, its association with ventricular drain obstruction remains unproven.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria : Patient older than 18 years old, * admitted to the ICU, * with first EVD inserted for less than 12 hours, * and brain imaging (CT or MRI) available in the timespan "24 hours before to 24 hours after" the EVD insertion. Exclusion Criteria : * EVD intentionally occluded immediately after its insertion, * purulent cerebrospinal fluid * Pregnant or breast-feeding patient * Moribund patient or patient with decision of withholding or withdrawing life-sustaining treatment within the 12 hours * Patient with no health insurance * Patient under guardianship

What they're measuring

Assessment of the predictive value of IVH severity for EVD obstruction

Timeframe: From EVD insertion to removal up to 100 days.

Trial details

NCT IDNCT06466811

SponsorNantes University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-12-01

Contact for this trial

Karim LAKHAL, PH

33 2 53 48 27 85 karim.lakhal@chu-nantes.fr