RecruitingPhase 2/3

Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis

Egypt36 participantsStarted 2022-06-01

Plain-language summary

The objective of this study is to investigate "clinically" the effectiveness of Boswellia based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

Who can participate

Age range20 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Single-rooted with pulp necrosis and apical periodontitis. * The age range from 20 to 60 years Exclusion Criteria: * Receiving antibiotic treatment within the preceding 3 months. * Reporting systemic disease. * Teeth that could not be isolated with rubber dam. * Teeth with periodontal pockets deeper than 3 mm.

What they're measuring

Microbiological culture (manual counting to bacterial cells)

Timeframe: up to 8 months

Trial details

NCT IDNCT06466538

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-01

Contact for this trial

May Abuzoor, phD

0096599182767 drmayzoor@hotmail.com

View on ClinicalTrials.gov More Microbial Colonization trials